Drug Evaluation Committee Overview and Notes on Network Meta-Analysis With reference to ISPOR Report (2011)

Data Science Subcommittee

November 2019

The Pharmaceutical Evaluation Committee's Data Science Subcommittee TF4 of 2019 summarizes the overview and notes on network meta-analysis.
Network meta-analysis is a methodology that allows direct drug-to-drug comparisons (direct comparisons) as well as indirect drug-to-drug comparisons (indirect comparisons) for outcomes such as efficacy and safety of drugs, based on the results of multiple studies. In recent years, cases of indications have been reported, and the results are considered to be used as information for the formulation of treatment guidelines and medical policy decisions. On the other hand, there are some points to keep in mind when using this methodology, such as its complexity. This NMA report provides an overview of network meta-analysis and points to keep in mind, referring to a report published by ISPOR (International Society for Pharmacoeconomics and Outcomes Research) in 2011.

NMA Report_20191110_Published (1.2MB)

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