Filaria/Dengue fever

Lymphatic filaria

Free Provision of Lymphatic Filariasis Drugs and Diagnostic Kits	In November 2010, Eisai agreed to provide the World Health Organization (WHO) with diethylcarbamazine (DEC), a medicine for lymphatic filariasis, free of charge. Based on this agreement, we manufactured DEC tablets at our own plant in India and began providing DEC tablets to countries where lymphatic filariasis is endemic in October 2013. In February 2016, a public-private partnership was launched to evaluate the achievement of LF control through mass drug administration (MDA) of filariasis drugs and to provide free diagnostic kits for use in determining when to terminate MDA. Eisai is contributing to the global lymphatic filariasis control program through the supply of DEC tablets and diagnostic kits.
Development of a drug for filariasis	Eisai is collaborating with the Liverpool School of Tropical Medicine and the University of Liverpool on the creation of new filarial anthelmintics effective against lymphatic filariasis and river blindness, the two major filariasis diseases. The Borrelia bacteria present in the body of adult filarial worms, which cause filariasis, are essential for the growth, proliferation, and survival of adult filarial worms.

Free Provision of Lymphatic Filariasis Drugs and Diagnostic Kits

In November 2010, Eisai agreed to provide the World Health Organization (WHO) with diethylcarbamazine (DEC), a medicine for lymphatic filariasis, free of charge. Based on this agreement, we manufactured DEC tablets at our own plant in India and began providing DEC tablets to countries where lymphatic filariasis is endemic in October 2013. In February 2016, a public-private partnership was launched to evaluate the achievement of LF control through mass drug administration (MDA) of filariasis drugs and to provide free diagnostic kits for use in determining when to terminate MDA. Eisai is contributing to the global lymphatic filariasis control program through the supply of DEC tablets and diagnostic kits.

Development of a drug for filariasis

Eisai is collaborating with the Liverpool School of Tropical Medicine and the University of Liverpool on the creation of new filarial anthelmintics effective against lymphatic filariasis and river blindness, the two major filariasis diseases. The Borrelia bacteria present in the body of adult filarial worms, which cause filariasis, are essential for the growth, proliferation, and survival of adult filarial worms.

Dengue fever

Development of dengue fever vaccine	Takeda is conducting a Phase III clinical trial (TIDES study) with the aim of evaluating the efficacy of two doses of quadrivalent attenuated attenuated dengue fever (TAK-003) against all four types of dengue viruses. The 18-month data from the TIDES study, which was obtained at 18 months of follow-up after the second dose of TAK-003 was administered 3 months after the first dose, showed efficacy in preventing virologically confirmed dengue fever infection (VCD) in children and young adults aged 4 to 16 years. The drug is already approved in Indonesia, the European Union, and other countries, and will continue to be submitted for approval in other dengue-endemic countries in Latin America and Asia. It has been launched in Germany, Austria, and the Czech Republic.

Development of dengue fever vaccine

Takeda is conducting a Phase III clinical trial (TIDES study) with the aim of evaluating the efficacy of two doses of quadrivalent attenuated attenuated dengue fever (TAK-003) against all four types of dengue viruses. The 18-month data from the TIDES study, which was obtained at 18 months of follow-up after the second dose of TAK-003 was administered 3 months after the first dose, showed efficacy in preventing virologically confirmed dengue fever infection (VCD) in children and young adults aged 4 to 16 years. The drug is already approved in Indonesia, the European Union, and other countries, and will continue to be submitted for approval in other dengue-endemic countries in Latin America and Asia. It has been launched in Germany, Austria, and the Czech Republic.

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Filaria/Dengue fever

Lymphatic filaria

Dengue fever

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